Impact of Elevated Adrenocorticotropic Hormone Levels in Pregnant Women with Gestational Hypertension

الملخص

Pregnancy-induced hypertension represents a significant public health issue due to its potential adverse
effects on both maternal and fetal outcomes. Adrenocorticotropic hormone (ACTH), a key regulator of
various physiological processes including blood pressure, has been proposed as a possible contributor to
the development of gestational hypertension when present at elevated levels during pregnancy. This study
explored the relationship between ACTH concentrations and blood pressure in pregnant women, with the
aim of assessing its influence on maternal health. Thirty pregnant women were enrolled, from whom blood
samples were obtained to determine ACTH levels, while blood pressure was monitored throughout
pregnancy. The results demonstrated a significant association between elevated ACTH concentrations and
increased systolic and diastolic blood pressure. Participants with higher ACTH levels consistently
exhibited greater blood pressure values compared to those with normal levels. Additional factors such as
age, body mass index, and gestational age were incorporated into the analysis to enhance reliability.
Although elevated ACTH appears to be a potential contributor to gestational hypertension, no statistically
significant differences were observed in liver function or other biochemical parameters between the
comparison groups.